WebFeb 25, 2024 · In multiple myeloma, genomic analysis shows a variety of gene mutations, aneuploidies, segmental copy-number changes, translocations that are extremely … WebApr 6, 2024 · Despite significant advancements in multiple myeloma (MM) therapy, the highly heterogenous treatment response hinders reliable prognosis and tailored therapeutics. Herein, we have studied the clinical utility of miRNAs in ameliorating patients’ management. miRNA-seq was performed in bone marrow CD138+ plasma cells (PCs) of …
Biological aspects of multiple myeloma - PubMed
WebJul 10, 2009 · Multiple myeloma is associated with a wide array of renal diseases that include myeloma cast nephropathy, monoclonal immunoglobulin deposition disease, amyloidosis, cryoglobulinemia, ... who presented with biochemical features consistent with Fanconi syndrome. Immunoelectron microscopy performed on the renal biopsy … WebApr 8, 2024 · Multiple Myeloma (MM) remains a difficult to treat disease mainly due to its biological heterogeneity, of which we are more and more knowledgeable thanks to the development of increasingly sensitive molecular methods that allow us to build better prognostication models. The biological diversity translates into a wide range of clinical … pop music high school
IgD multiple myeloma: Clinical, biological features and
WebAug 7, 2024 · Management of Myeloma Biochemical Progression. Aug 7, 2024. Sagar Lonial, MD: This is a case of an elderly, frail gentleman who presented with symptomatic myeloma. He was initially started on lenalidomide and dexamethasone with appropriate reductions in the lenalidomide dose based on renal function, as well as overall … WebDec 30, 2024 · Multiple myeloma (MM) is a clonal proliferation of plasma cells invading the bone marrow and secreting monoclonal immunoglobulin. In order to study the epidemiological and biological and ... WebMay 25, 2016 · Multiple myeloma is a cancer that begins in plasma cells, a type of white blood cell. These cells are part of your immune system, which helps protect the body … pop music hits 2021