Htatsf1 topbp1

Author: tcip

August undefined, 2024

Webp53 Binding protein 1 (53BP1) belongs to a family of evolutionarily conserved DNA damage checkpoint proteins with C-terminal BRCT domains and is most likely the human ortholog … Web4 feb. 2024 · TOPBP1 was immobilized on Dynabeads Protein G coupled with anti-TOPBP1 antibody, and the interaction assay was performed at 100 mM NaCl. The indicated protein was analyzed by Western blotting. (F) Phosphorylation landscape of BLM upon in vitro treatment with CDK2-CycA and PLK1, with or without TOPBP1, as indicated.

DNA damage response protein TOPBP1 regulates X chromosome …

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WebOnce ATR is engaged on the RPA-ssDNA, it could at least phosphorylate itself (), while the full activation of ATR requires multiple regulators including RAD17, 9-1-1 complex, and … Web1 jul. 2015 · (E) Topbp1 MO can block the translation of topbp1 mRNA. The topbp1 MO, as validated in S3 Fig, was injected into one-cell stage wild-type embryos to produce … WebFor Flag-TopBP1 transfection, cells were plated 24 h before transfection in 100 mm dishes at 1 × 10 6 cells. 12.5 μg of pcDNA3-TopBP1 was mixed with 25 μl of Polyethylenimine … smith haven mall macy\u0027s

Full article: Human CTC1 promotes TopBP1 stability and CHK1 ...

Htatsf1 topbp1

Coordinated Control of mRNA and rRNA Processing ... - Cell Stem Cell

Web21 jul. 2024 · HTATSF1 is an S-phase-specific interactor of TOPBP1 (A) Immunostaining and confocal microscopy analysis of the foci formation of the indicated TOPBP1 variants … WebTOPBP1 Antibodies. Antibodies that detect TOPBP1 can be used in several scientific applications, including Western Blot, Immunocytochemistry, Immunohistochemistry, …

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WebHTATSF1 Gene. HTATSF1. The protein encoded by this gene functions as a cofactor for the stimulation of transcriptional elongation by HIV-1 Tat, which binds to the HIV-1 promoter through Tat-TAR interaction. This protein may also serve as a dual-function factor to couple transcription and splicing and to facilitate their reciprocal activation. WebPEPTIDE AA LOCATION: HTATSF1 peptide corresponds to 15 amino acids of HTATSF1. SPECIES: Human TESTED APPLICATIONS: Blocking APPLICATION NOTE: HTATSF1 …

WebZhao et al. reveal that HTATSF1 forms a complex with TOPBP1 in a cell-cycle- and phosphorylation-dependent manner and assigns TOPBP1 to resected DNA ends through … WebThe Virtual Health Library is a collection of scientific and technical information sources in health organized, and stored in electronic format in the countries of the Region of Latin …

Web3 okt. 2024 · Human TopBP1 plays essential roles in DNA replication initiation, checkpoint signaling, and DNA repair and influences transcriptional control ( 3, 4 ). TopBP1 contains eight BRCA1 carboxyl-terminal (BRCT) phosphopeptide recognition motifs and an ATR-activating domain (AAD) ( 3, 4 ).

Web21 jul. 2024 · HTATSF1 is an RNA-binding protein, and its RRMs are essential for the recruitment of TOPBP1. By inhibiting transcription and not observing a phenotype, the …

WebTogether, our study provides a mechanistic insight into TOPBP1 loading at HR-prone DSB sites via HTATSF1 and reveals how RPA-RAD51 exchange is tuned by a PARylation … smith haven mall pet pictures with santaWebPMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 35597237-5 2024 The localization of HTATSF1-TOPBP1 to DSBs is … smith haven mall lake groveWeb21 jul. 2024 · HTATSF1 is an RNA-binding protein, and its RRMs are essential for the recruitment of TOPBP1. By inhibiting transcription and not observing a phenotype, the … rival pages one getting in on timeWeb14 okt. 2024 · HTATSF1-Nucleated PARylation and Phosphorylation Cascade Dictates Homologous Recombination and Modulates Chemotherapeutic Response of Breast … rival peak facebookWeb2 aug. 2024 · We report that TOPBP1 is only transiently present at DSBs, with a half-life of less than 10 minutes. We also examined the relationship between TOPBP1 and the … smith haven mall map directoryWeb5 mei 2024 · 7 State Key Laboratory of Medicinal Chemical Biology, College of Pharmacy and Key Laboratory of Medical Data Analysis and Statistical Research of Tianjin, Nankai … rival penelope douglas read onlineWebThe Virtual Health Library is a collection of scientific and technical information sources in health organized, and stored in electronic format in the countries of the Region of Latin America and the Caribbean, universally accessible on the Internet and compatible with international databases. rival pearl jam lyrics